Hyperthermia Blog

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The 2020 ESHO-Pyrexar Award presentation included the history and merits of Professor Niloy Datta, celebrating his achievements in the field of thermal oncology.  What follows the award presentation is nothing less than a Master Class in thermal oncology.  Dr. Datta shares highlights of his research and his vision for the pathway to hyperthermia expansion and success.

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Along with presenting evidence of the increased value to the patient that hyperthermia brings, Dr. Datta also touches on the financial rationale of adding a thermal oncology program to your hospital.

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Below find a summary of recently published works involving hyperthermia by Datta et al.

Concurrent chemoradiotherapy vs. radiotherapy alone in locally advanced cervix cancer: A systematic review and meta-analysis.
Datta NR, Stutz E, Liu M, Rogers S, Klingbiel D, Siebenhüner A, Singh S, Bodis S.
Gynecol Oncol. 2017 May;145(2):374-385. doi: 10.1016/j.ygyno.2017.01.033. Epub 2017 Feb 7.
PMID: 28188016 Review.
Integrating Loco-Regional Hyperthermia Into the Current Oncology Practice: SWOT and TOWS Analyses.
Datta NR, Kok HP, Crezee H, Gaipl US, Bodis S.
Front Oncol. 2020 Jun 12;10:819. doi: 10.3389/fonc.2020.00819. eCollection 2020.
PMID: 32596144 Free PMC article. Review.
Hyperthermia and radiotherapy in bladder cancer.
Snider JW 3rd, Datta NR, Vujaskovic Z.
Int J Hyperthermia. 2016 Jun;32(4):398-406. doi: 10.3109/02656736.2016.1150524. Epub 2016 Apr 20.
PMID: 27097528 Review.
Hyperthermia with radiotherapy reduces tumour alpha/beta: Insights from trials of thermoradiotherapy vs. radiotherapy alone.
Datta NR, Bodis S.
Radiother Oncol. 2019 Sep;138:1-8. doi: 10.1016/j.radonc.2019.05.002. Epub 2019 May 24.
PMID: 31132683
Hyperthermia with photon radiotherapy is thermoradiobiologically analogous to neutrons for tumors without enhanced normal tissue toxicity.
Datta NR, Bodis S.
Int J Hyperthermia. 2019;36(1):1073-1078. doi: 10.1080/02656736.2019.1679895.
PMID: 31709846
Early results and volumetric analysis after spot-scanning proton therapy with concomitant hyperthermia in large inoperable sacral chordomas.
Tran S, Puric E, Walser M, Poel R, Datta NR, Heuberger J, Pica A, Marder D, Lomax N, Bolsi A, Morach P, Bachtiary B, Seddon BM, Schneider R, Bodis S, Weber DC.
Br J Radiol. 2020 Mar;93(1107):20180883. doi: 10.1259/bjr.20180883. Epub 2019 May 14.
PMID: 30943055
A Pilot Study of Radiotherapy and Local Hyperthermia in Elderly Patients With Muscle-Invasive Bladder Cancers Unfit for Definitive Surgery or Chemoradiotherapy.
Datta NR, Stutz E, Puric E, Eberle B, Meister A, Marder D, Timm O, Rogers S, Wyler S, Bodis S.
Front Oncol. 2019 Sep 10;9:889. doi: 10.3389/fonc.2019.00889. eCollection 2019.
PMID: 31552192 Free PMC article.
Local hyperthermia combined with radiotherapy and-/or chemotherapy: recent advances and promises for the future.
Datta NR, Ordóñez SG, Gaipl US, Paulides MM, Crezee H, Gellermann J, Marder D, Puric E, Bodis S.
Cancer Treat Rev. 2015 Nov;41(9):742-53. doi: 10.1016/j.ctrv.2015.05.009. Epub 2015 May 27.
PMID: 26051911 Review.
Hyperthermia and radiotherapy in the management of head and neck cancers: A systematic review and meta-analysis.
Datta NR, Rogers S, Ordóñez SG, Puric E, Bodis S.
Int J Hyperthermia. 2016;32(1):31-40. doi: 10.3109/02656736.2015.1099746. Epub 2015 Nov 16.
PMID: 26928474 Review.
Hyperthermia and Radiation Therapy in Locoregional Recurrent Breast Cancers: A Systematic Review and Meta-analysis.
Datta NR, Puric E, Klingbiel D, Gomez S, Bodis S.
Int J Radiat Oncol Biol Phys. 2016 Apr 1;94(5):1073-87. doi: 10.1016/j.ijrobp.2015.12.361. Epub 2015 Dec 21.
PMID: 26899950 Review.
Hyperthermia and radiotherapy with or without chemotherapy in locally advanced cervical cancer: a systematic review with conventional and network meta-analyses.
Datta NR, Rogers S, Klingbiel D, Gómez S, Puric E, Bodis S.
Int J Hyperthermia. 2016 Nov;32(7):809-21. doi: 10.1080/02656736.2016.1195924. Epub 2016 Aug 14.
PMID: 27411568 Review.
Proton Irradiation with Hyperthermia in Unresectable Soft Tissue Sarcoma.
Datta NR, Schneider R, Puric E, Ahlhelm FJ, Marder D, Bodis S, Weber DC.
Int J Part Ther. 2016 Fall;3(2):327-336. doi: 10.14338/IJPT-16-00016.1. Epub 2016 Dec 30.
PMID: 31772984 Free PMC article.
Could hyperthermia with proton therapy mimic carbon ion therapy? Exploring a thermo-radiobiological rationale.
Datta NR, Puric E, Schneider R, Weber DC, Rogers S, Bodis S.
Int J Hyperthermia. 2014 Nov;30(7):524-30. doi: 10.3109/02656736.2014.963703. Epub 2014 Oct 14.
PMID: 25314095
Hyperthermia and reirradiation for locoregional recurrences in preirradiated breast cancers: a single institutional experience.
Datta NR, Puric E, Heüberger J, Marder D, Lomax N, Timm O, Memminger P, Bodis S.
Swiss Med Wkly. 2015 Apr 23;145:w14133. doi: 10.4414/smw.2015.14133. eCollection 2015.
PMID: 25906357
"HEATPAC" - a phase II randomized study of concurrent thermochemoradiotherapy versus chemoradiotherapy alone in locally advanced pancreatic cancer.
Datta NR, Pestalozzi B, Clavien PA, Siebenhüner A, Puric E, Khan S, Mamot C, Riesterer O, Knuchel J, Reiner CS, Bodis S; members of the HEATPAC Trial Group.
Radiat Oncol. 2017 Nov 21;12(1):183. doi: 10.1186/s13014-017-0923-8.
PMID: 29162142 Free PMC article. Clinical Trial.
Enhanced tumour regression in a patient of liposarcoma treated with radiotherapy and hyperthermia: Hint for dynamic immunomodulation by hyperthermia.
Datta NR, Grobholz R, Puric E, Bode-Lesniewska B, Lomax N, Khan S, Gaipl US, Fuchs B, Bodis S.
Int J Hyperthermia. 2015;31(5):574-7. doi: 10.3109/02656736.2015.1033482. Epub 2015 Apr 20.
PMID: 25893831 No abstract available.

 A special thanks to Dr. Sennewald Medizintechnik for sponsoring the award and presentation.