Hyperthermia Blog

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Clinical Studies Still In Process

Details

Medical news may be dominated by pandemic coverage, but cancer research still moves forward.  We did a quick search on clinicaltrials.gov for trials using hyperthermia as an adjunct to radiotherapy, chemotherapy, and immunotherapy.  The listing below is a summary of studies around the world. 

Clinical Study Indication Facility Country  Pyrexar Installation
Hyperthermia and High Dose Rate Radiation Therapy in Treating Patients With Recurrent Prostate Cancer After Radiation Prostate Cancer Sidney Kimmel Cancer Center at Thomas Jefferson University USA ✔ 
Hyperthermia and Proton Therapy in Unresectable Soft Tissue Sarcoma Soft Tissue Sarcoma Kantonsspital Aarau Switzerland ✔
Effectiveness of the Combined WLI and Hyperthermia for GI Cancer Liver Metastasis Metastatic Liver Cancer Samsung Medical Center South Korea  
Hypofractionated Radiotherapy With Hyperthermia in Unresectable or Marginally Resectable Soft Tissue Sarcomas Soft Tissue Sarcoma Maria Sklodowska-Curie Institute - Oncology Center Poland  ✔
Combination of Hyperthermia and Concurrent Chemoradiotherapy (CCRT) for Recurrent Head and Neck Cancer Head/Neck Shin Kong Wu Ho-Su Memorial Hospital Taiwan  
Radiotherapy With Hyperthermia in Recurrent and Radiation-Induced Sarcomas Sarcoma Maria Sklodowska-Curie National Research Institute of Oncology  Poland  ✔
Preoperative Radiochemotherapy With Hyperthermia for Locally Advanced Rectal Cancer Rectal Cancer University Hospital Tübingen Germany  ✔
Salvage Brachytherapy and Hyperthermia for Recurrent H&N-tumours Head/Neck Cancer Sidney Kimmel Cancer Center at Thomas Jefferson University  United States  ✔
Local Hyperthermia for the Treatment of Cervical Intraepithelial Neoplasias Cervical Cancer First Hospital of China Medical University China  
Image-guided Targeted Doxorubicin Delivery With Hyperthermia to Optimize Loco-regional Control in Breast Cancer Breast Cancer University Medical Center Utrecht Netherlands  
Hyperthermia European Adjuvant Trial Pancreatic Cancer Klinikum Grosshadern Medical Center Germany ✔
Salvage Brachytherapy and Interstitial Hyperthermia for Locally Recurrent Prostate Carcinoma Following Radiation Therapy

 Prostate Cancer
 		 Strahlenklinik im Universitaetsklinikum Erlangen Germany

  ✔
 Centrum Radiotherapy  Poland  ✔
 Maria Sklodowska-Curie Institute - Oncology Center  Poland  ✔
Effects of Deep Regional Hyperthermia in Patients With Anal Carcinoma Treated by Standard Radiochemotherapy Anal Cancer Universitaetsklinikum Erlangen Germany  ✔
Concurrent Hyperthermia and Chemoradiotherapy in LAPC: Phase II Study Pancreatic Cancer Kantonsspital Aarau Switzerland  ✔
Neoadjuvant Chemoradiation With 5-FU(or Capecitabine) and Oxaliplatin Combined With Hyperthermia in Rectal Cancer


 Rectal Cancer   Klinik Bad Trissl  Germany   ✔
Bad Trissl  Germany  ✔
 University Hospital Duesseldorf  Germany  ✔
 Universitätsklinikum Erlangen  Germany  ✔
Radiation Therapy or Chemoradiation Interstitial Brachytherapy in Combination With Hyperthermia in Advanced Cervical Cancer Cervical Cancer Universitätsklinikum Erlangen Germany  ✔
Combination of Immunotherapy and Hyperthermia in Advanced Malignant Mesothelioma Mesothelioma Capital Medical University Cancer Center China  
Regional hyperthermia and salvage radiotherapy is being tested in patients with biochemically recurrent prostate cancer after radical prostatectomy Prostate Cancer Universitätsklinikum Tübingen  Germany  ✔
Universitätsklinikum Erlangen  Germany  ✔
Charité Universitätsmedizin Germany  ✔
Organ Preservation in Locally Advanced Rectal Cancer by Radiochemotherapy Followed by Consolidation Chemotherapy    Rectal Cancer    University Hospital Erlangen   Germany ✔ 
University Hospital Frankfurt  Germany  
University Hospital Tübingen Germany  ✔
University Hospital Würzburg Germany  

HIPEC studies have not been included in this list. Listing facilities with Pyrexar hyperthermia systems is not a statement that those systems are used in the study, only that they exist at the facilities conducting the study.  If you know of a study not included in the list, please let us know, and we would be happy to share it on our website.